PAPER Jiang Y, Lin Y, Tetlow AM, Pan R, Ji C, Kong X-P, Congdon EE, Sigurdsson EM

Single-Domain Antibody-Based Protein Degrader for Synucleinopathies

bioRxiv2024.03.11.584473

Tina Johnson

Grand Forks, United States

Joshua Emmerson

Washington University St Louis
Saint Louis, United States

Dhanya Mol

assistant professor on contract
Nadathara, India

In AD, Effects of Some Genetic Variants Limited to Cell Subtypes

RESEARCH NEWS 2024-03-27 Research News While genome-wide association studies tie variants to disease risk, they don’t explain how those variants influence gene expression or pathology. In the March 21 Nature Genetics, scientists led by Vilas Menon and Philip De Jager at New York’

PAPER Yang H, Kim J, Kim Y, Jang SW, Sestan N, Shim S

Cux2 expression regulated by Lhx2 in the upper layer neurons of the developing cortex.

Biochem Biophys Res Commun. 2020 Jan 22;521(4):874-879. Epub 2019 Nov 8 PubMed: 31708105

Darcy Adreon

University of Kentucky
Lexington, United States

Hillary Rouse

Steven Clapcote

University of Leeds
United Kingdom

PAPER Ohgita T, Sakai K, Fukui N, Namba N, Nakano M, Kiguchi Y, Morita I, Oyama H, Yamaki K, Nagao K, Kobayashi N, Saito H

Generation of novel anti-apoE monoclonal antibodies that selectively recognize apoE isoforms.

FEBS Lett. 2024 Apr;598(8):902-914. Epub 2024 Mar 26 PubMed: 38529702

PAPER Zhu W, Zhou J, Shang L, Zhou Y, Wang Q, Yu Y, Dong L, Mao C, Chu S, Jin W, Li J, Gao J

Generation and characterization of an iPS cell line (PUMCi006-A) from skin fibroblasts of a patient with an M239T mutation in PSEN2 gene.

Stem Cell Res. 2024 Mar 14;77:103391. PubMed: 38531230

PAPER Zhang J, Cui X, Zhao S, Chang Z, Zhang J, Chen Y, Liu J, Sun G, Wang Y, Liu Y

Establishment of a pharmacokinetics and pharmacodynamics model of Schisandra lignans against hippocampal neurotransmitters in AD rats based on microdi-alysis liquid chromatography-mass spectrometry.

Front Pharmacol. 2024;15:1342121. Epub 2024 Mar 11 PubMed: 38529184

PAPER Faquetti ML, Slappendel L, Bigonne H, Grisoni F, Schneider P, Aichinger G, Schneider G, Sturla SJ, Burden AM

Baricitinib and tofacitinib off-target profile, with a focus on Alzheimer's disease.

Alzheimers Dement (N Y). 2024;10(1):e12445. Epub 2024 Jan 26 PubMed: 38528988

PAPER Wang L, Qu F, Yu X, Yang S, Zhao B, Chen Y, Li P, Zhang Z, Zhang J, Han X, Wei D

Cortical lipid metabolic pathway alteration of early Alzheimer's disease and candidate drugs screen.

Eur J Med Res. 2024 Mar 25;29(1):199. PubMed: 38528586

PAPER Velasco-Rodríguez LD, García HS, Rascón-Díaz MP

Curcumin and omega-3 polyunsaturated fatty acids as bioactive food components with synergistic effects on Alzheimer's disease.

Psychogeriatrics. 2024 Mar 25; PubMed: 38528391